Ocular rigidity and outflow facility in nonproliferative diabetic retinopathy

To compare ocular rigidity (or) and outflow facility (c) in patients with nonproliferative diabetic retinopathy (npdr) and control subjects. methods. twenty-four patients with npdr (npdr group) and 24 controls (control group) undergoing cataract surgery were enrolled. npdr group was further divided into patients with mild npdr (npdr1-group) and patients with moderate and/or severe npdr (npdr2-group). after cannulation of the anterior chamber,a computer-controlled device was used to infuse saline and increase the intraocular pressure (iop) in a stepping procedure from 15 to 40 mmhg. ocular rigidity and outflow facility coefficients were estimated from iop and volume recordings. results. ocular rigidity was 0.0205 l-1 in npdr group and 0.0202 μ l-1 in control group (p=0.942). in npdr1-group,or was 0.017μ l-1 and in npdr2-group it was 0.025 μl-1 (p=0.192). outflow facility was 0.120 μl/min/mmhg in npdr-group compared to 0.153 l/min/mmhg in the control group at an iop of 35 mmhg (p=0.151). there was no difference in c between npdr1-group and npdr2-group (p=0.709). conclusions. no statistically significant differences in ocular rigidity and outflow facility could be documented between diabetic patients and controls. no difference in or and c was detected between mild npdr and severe npdr. © 2015 theonitsa panagiotoglou et al.