|
|
|
|
Vitamin D deficiency is associated with the presence and severity of diabetic retinopathy in type 2 diabetes mellitus
|
|
|
|
|
|
|
|
نویسنده
|
alcubierre n. ,valls j. ,rubinat e. ,cao g. ,esquerda a. ,traveset a. ,granado-casas m. ,jurjo c. ,mauricio d.
|
|
منبع
|
journal of diabetes research - 2015 - دوره : 2015 - شماره : 0
|
|
چکیده
|
There is very few evidences on the role of vitamin d in the development of diabetic retinopathy. the aim of the current study was to explore whether there is an association of vitamin d status and diabetic retinopathy in type 2 diabetes. two groups of patients were selected: 139 and 144 patients with and without retinopathy,respectively,as assessed by an experienced ophthalmologist. subjects with advanced late diabetic complications were excluded to avoid confounding biases. 25-hydroxy-vitamin d3 (25(oh)d) concentrations and vitamin d deficiency were associated with the presence of diabetic retinopathy. additionally,patients with more advanced stages of retinopathy (grades 2-4) had lower concentrations of 25(oh)d and were more frequently vitamin d deficient as compared with patients not carrying this eye complication. in conclusion,our study confirms the association of vitamin d deficiency with the presence and severity of diabetic retinopathy in type 2 diabetes. further experimental and prospective studies on this issue are clearly warranted. © 2015 nuria alcubierre et al.
|
|
|
|
|
آدرس
|
biomedical research institute of lleida,university of lleida,rovira roure 80, Spain, biostatistics and epidemiology unit,biomedical research institute of lleida,university of lleida,rovira roure 80, Spain, biomedical research institute of lleida,university of lleida,rovira roure 80,lleida,spain,department of endocrinology and nutrition,university hospital arnau de vilanova,rovira roure 80, Spain, department of laboratory medicine,university hospital arnau de vilanova,rovira roure 80, Spain, department of laboratory medicine,university hospital arnau de vilanova,rovira roure 80, Spain, department of ophthalmology,university hospital arnau de vilanova,rovira roure 80, Spain, biomedical research institute of lleida,university of lleida,rovira roure 80, Spain, department of ophthalmology,university hospital arnau de vilanova,rovira roure 80, Spain, biomedical research institute of lleida,university of lleida,rovira roure 80,lleida,spain,department of endocrinology and nutrition,health sciences research institute,university hospital germans trias i pujol,carretera canyet s/n, Spain
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|