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   Synthesis and antimicrobial activity of carboxylate phosphabetaines derivatives with alkyl chains of various lengths  
   
نویسنده galkina i.v. ,bakhtiyarova y.v. ,shulaeva m.p. ,pozdeev o.k. ,egorova s.n. ,cherkasov r.a. ,galkin v.i.
منبع journal of chemistry - 2013 - دوره : 2013 - شماره : 0
چکیده    The purpose of the present study was to investigate the antibacterial activity of fifteen novel nanosized alkyl esters of carboxylate phosphabetaine: β-(carboxyalkyl)ethyltriphenylphosphonium bromides 4-8,β-(carboxyalkyl)-β-methylethyltriphenylphosphonium bromides 9-13,and β-(carboxyalkyl)-α-methylethyltriphenylphosphonium bromides 14-18. the in vitro microbiological activity of the synthesized phosphonium bromides against gram-positive and gram-negative bacteria and the yeast candida albicans was determined in comparison to standard agents. microbiological results indicate that the synthesized phosphonium salts 4-18 possess a broad spectrum of activity against the tested microorganisms. every newly synthesized compound was characterized by elemental analyses,ir,1h nmr,and 31p nmr spectral studies. © 2013 irina v. galkina et al.
آدرس department of high molecular and organoelement compounds,a. m. butlerov chemistry institute,kazan federal university, Russian Federation, department of high molecular and organoelement compounds,a. m. butlerov chemistry institute,kazan federal university, Russian Federation, department of microbiology,kazan state medical academy, Russian Federation, department of microbiology,kazan state medical academy, Russian Federation, department of pharmacology,kazan state medical university, Russian Federation, department of high molecular and organoelement compounds,a. m. butlerov chemistry institute,kazan federal university, Russian Federation, department of high molecular and organoelement compounds,a. m. butlerov chemistry institute,kazan federal university, Russian Federation
 
     
   
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