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Synthesis and characterization of process-related impurities of antihypertensive drug olmesartan medoxomil
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نویسنده
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venkanna g. ,madhusudhan g. ,mukkanti k. ,sankar a. ,sampath kumar y. ,venakata narayana g.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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Olmesartan medoxomil (1) is the latest angiotensin receptor antagonist approved by the fda for the treatment of hypertension. during the process development of olmesartan medoxomil,three process-related impurities were observed along with the final api. these impurities were identified as isopropyl olmesartan (12),dimedoxomil olmesartan (19),dibiphenyl olmesartan (17). the present work describes the synthesis and characterization of all these three impurities. © 2013 g. venkanna et al.
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آدرس
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department of research and development,inogent laboratories private limited,28a,ida,nacharam,hyderabad 500 076,india,centre for pharmaceutical sciences,institute of science and technology,jawaharlal nehru technological university,kukatpally, India, department of research and development,inogent laboratories private limited,28a,ida,nacharam, India, centre for pharmaceutical sciences,institute of science and technology,jawaharlal nehru technological university,kukatpally, India, department of research and development,inogent laboratories private limited,28a,ida,nacharam, India, department of research and development,inogent laboratories private limited,28a,ida,nacharam, India, department of research and development,inogent laboratories private limited,28a,ida,nacharam, India
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Authors
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