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Fabrication of heparinized mesoporous silica nanoparticles as multifunctional drug carriers
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نویسنده
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zhang y. ,liu x. ,lu y. ,wang j. ,dong t. ,liu x.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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In this study,heparinized multifunctional mesoporous silica nanoparticles were successfully synthesized and characterized. the new material not only maintains intrinsic functions of bare magnetic and fluorescent mesoporous silica materials such as targeting,imaging,and sustained release of drugs,but also generates several novel activities such as the enhancement of biocompatibility,selective loading drugs,and dual loading of anticancer drug and bfgf,rendering it a promising candidate to be used as a multifunctional carrier. the strategy of combination of multifunctional mesoporous silica materials with bioactive molecules could be a new effective approach to improve their capabilities in the drug delivery. © 2013 yongxiang zhang et al.
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آدرس
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first affiliated hospital,xinxiang medical university, China, first affiliated hospital,xinxiang medical university, China, first affiliated hospital,xinxiang medical university, China, first affiliated hospital,xinxiang medical university, China, first affiliated hospital,xinxiang medical university, China, first affiliated hospital,xinxiang medical university, China
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Authors
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