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Acetylcholinesterase inhibitory activities of flavonoids from the leaves of ginkgo biloba against brown planthopper
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نویسنده
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ding x. ,ouyang m.-a. ,liu x. ,wang r.-z.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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Ginkgo biloba is a traditional chinese medicinal plant which has potent insecticidal activity against brown planthopper. the meoh extract was tested in the acetylcholinesterase (ache) inhibitory assay with ic50 values of 252.1 g/ml. two ginkgolides and thirteen flavonoids were isolated from the leaves of ginkgo biloba. their structures were established on the basis of spectroscopic data interpretation. it revealed that the 13 isolated flavonoids were found to inhibit ache with ic50 values ranging from 57.8 to 133.1 g/ml in the inhibitory assay. ache was inhibited dose dependently by all tested flavonoids,and compound 6 displayed the highest inhibitory effect against ache with ic50 values of 57.8 g/ml. © 2013 xiao ding et al.
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آدرس
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key laboratory of bio-pesticide and chemistry-biology,ministry of education,fujian agriculture and forestry university,fuzhou, China, institute of plant virology,fujian agriculture and forestry university,fuzhou, China, key laboratory of integrated pest management for fujian-taiwan crops,ministry of agriculture,fuzhou, China, key laboratory of bio-pesticide and chemistry-biology,ministry of education,fujian agriculture and forestry university,fuzhou, China
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Authors
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