Synthesis,spectroscopic characterization and biological activities of transition metal complexes derived from a tridentate schiff base

A new series of cu (ii),ni (ii),co (ii) and zn (ii) complexes have been synthesized from the schiff base derived from 4-hydroxy-3-methoxybenzylidine-4- aminoantipyrine and 2-aminophenol. the structural features have been determined from their elemental analysis,magnetic susceptibility,molar conductance,mass,ir,uv-vis,1h-nmr,13c-nmr and esr spectral studies. the redox behavior of the copper complex has been studied by cyclic voltammetry. the data confirm that the complexes have composition of ml2 type. the electronic absorption spectral data of the complexes propose an octahedral geometry around the central metal ion. all the metal complexes with dna structure were guided by the presence of inter-molecular c-h o and c-h n hydrogen bonds. the biological activity of the synthesized compounds were tested against the bacterial species such as bacillus subtilis,staphylococcus aureus,proteus vulgaris and fungal species such as candida albicans by the well-diffusion method. © 2013 j. senthil kumaran et al.