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Synthesis and X-ray crystal structure of (1 E)-1-(4-Chlorophenyl)- N -hydroxy-3-(1 H -imidazol-1-yl)propan-1-imine
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نویسنده
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attia m.i. ,ghabbour h.a. ,almutairi m.s. ,ghoneim s.w. ,abdel-aziz h.a. ,fun h.-k.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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Synthesis and characterization of (1 e)-1-(4-chlorophenyl)-n-hydroxy-3-(1 h -imidazol-1-yl)propan-1-imine (4) are reported. x-ray crystal structure of the title oxime 4 confirmed its assigned (e)-configuration. the compound crystallizes in the monoclinic space group p 21/c with a = 13.4292 (3) å,b = 8.8343 (2) å,c = 11.1797 (3) å,α = 90 °,β = 108.873 (2)°,γ = 90°,v = 1255.03 (5) å 3,and z = 4. the molecules are packed in crystal structure by weak intermolecular o - h n hydrogen bonding interactions. compound 4 is a useful intermediate for the synthesis of new imidazole-containing antifungal agents. © 2013 mohamed i. attia et al.
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آدرس
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department of pharmaceutical chemistry,college of pharmacy,king saud university,p.o. box 2457, Saudi Arabia, department of pharmaceutical chemistry,college of pharmacy,king saud university,p.o. box 2457, Saudi Arabia, department of pharmaceutical chemistry,college of pharmacy,king saud university,p.o. box 2457, Saudi Arabia, department of pharmaceutical chemistry,college of pharmacy,king saud university,p.o. box 2457, Saudi Arabia, department of pharmaceutical chemistry,college of pharmacy,king saud university,p.o. box 2457, Saudi Arabia, department of pharmaceutical chemistry,college of pharmacy,king saud university,p.o. box 2457, Saudi Arabia
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Authors
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