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Synthesis,antibacterial and antioxidant evaluation of novel 1-(5,7-dichloro-1,3-benzoxazol-2-yl)-1 H -pyrazolo[3,4-b]quinoline derivatives
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نویسنده
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jayanna n.d. ,vagdevi h.m. ,dharshan j.c. ,kekuda t.r.p.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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Some novel 1-(5,7-dichloro-1,3-benzoxazol-2-yl)-1h-pyrazolo[3,4-b]quinoline derivatives 8(a-f) were synthesized by reacting 5,7-dichloro-2-hydrazino-1,3- benzoxazole 4 and substituted-2-chloro-3-quinoline carbaldehydes using p-toluenesulfonic acid (ptsa) as a catalyst for the cyclisation. the target molecules have been characterized by ir,1h nmr,13c nmr,and mass spectral studies. the synthesized compounds were screened for biological activities,and some of the compounds have exhibited encouraging antibacterial and antioxidant activities. the compounds 8a and 8e showed potent antibacterial activity,whereas the compounds 8e and 8f act as antioxidants. © 2013 n. d. jayanna et al.
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آدرس
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department of chemistry,sahyadri science college, India, department of chemistry,sahyadri science college, India, department of pg studies and research in industrial chemistry,sir m.v. government science college,bommanakatte, India, department of microbiology,sahyadri science college, India
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Authors
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