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An efficient one-pot multicomponent synthesis of 4-Aza-podophyllotoxin derivatives in ionic liquid
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نویسنده
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naeimi h. ,rashid z. ,zarnani a.h. ,ghahremanzadeh r.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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A simple,green,and efficient procedure for the synthesis of 4-aza-podophyllotoxin derivatives by using a one-pot three-component reaction of benzaldehydes,1,3-cyclohexanediones,and anilinolactones in the presence of catalytic amount of alum in 1-butyl-3-methylimidazolium triflate as green media is described. this reaction proceeded under mild conditions with the use of an inexpensive and readily available catalyst,high to excellent yields,and simple workup procedure. © 2013 hossein naeimi et al.
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آدرس
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university of kashan, ایران, university of kashan, ایران, reproductive immunology research center,avicenna research institute,acecr, ایران, nanobiotechnology research center,avicenna research institute,acecr, ایران
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Authors
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