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Antibacterial,cytotoxic studies and characterization of some newly synthesized symmetrical N 3,N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes
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نویسنده
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jamil m. ,zubair m. ,asim farid m. ,rashid u. ,rasool n. ,islam s.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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A series of some novel n 3,n 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) compounds with general formula [c6h 4·{conhcsnhr}2],where r = 2-clc6h 4s (l1),3,5-(cl)2c6h3 (l2),2,4-(cl)2c6h3 (l3),2,5-(cl)2c6h3 (l4),and 2-nh 2c6h4 (l5),and their cu(ii) and ni(ii) complexes (c1-c10) have been synthesized. these compounds (l1-l5) and their metal(ii) complexes (c 1-c10) have been characterized by elemental analysis,infrared spectroscopy,1h nmr and 13c nmr spectroscopy,magnetic moments,and electronic spectral measurements. the ligands are coordinated to metal atom in a bidentate pattern producing a neutral complex of the type [ml]2. these compounds (l1-l5) and their metal(ii) complexes (c1-c10) were also screened for their antibacterial and cytotoxic activities. © 2013 muhammad jamil et al.
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آدرس
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department of chemistry,government college university, Pakistan, department of chemistry,government college university, Pakistan, institute of chemical sciences,bahauddin zakariya university, Pakistan, Universiti Putra Malaysia, Malaysia, department of chemistry,government college university, Pakistan, Universiti Putra Malaysia, Malaysia
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Authors
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