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HMG-CoA reductase inhibitors from Monascus -fermented rice
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نویسنده
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li x. ,liu c. ,duan z. ,guo s.
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منبع
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journal of chemistry - 2013 - دوره : 2013 - شماره : 0
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چکیده
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Seven compounds were isolated from monascus-fermented rice by column chromatography with silica gel and semiprep hplc. their structures were elucidated by extensive spectroscopic methods. all compounds displayed hmg-coa reductase inhibitory potential,among them compound 7 exhibited strong inhibition with ic50 value comparable with lovastatin. in this study,two compounds (1 and 2) were obtained from natural source for the first time. © 2013 xuemei li et al.
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آدرس
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beijing peking university,wbl biotechnology co.,ltd., China, beijing peking university,wbl biotechnology co.,ltd., China, beijing peking university,wbl biotechnology co.,ltd., China, beijing peking university,wbl biotechnology co.,ltd., China
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Authors
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