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   Imidazole: Having versatile biological activities  
   
نویسنده verma a. ,joshi s. ,singh d.
منبع journal of chemistry - 2013 - دوره : 2013 - شماره : 0
چکیده    Imidazoles have occupied a unique position in heterocyclic chemistry,and its derivatives have attracted considerable interests in recent years for their versatile properties in chemistry and pharmacology. imidazole is nitrogen-containing heterocyclic ring which possesses biological and pharmaceutical importance. thus,imidazole compounds have been an interesting source for researchers for more than a century. the imidazole ring is a constituent of several important natural products,including purine,histamine,histidine,and nucleic acid. being a polar and ionisable aromatic compound,it improves pharmacokinetic characteristics of lead molecules and thus is used as a remedy to optimize solubility and bioavailability parameters of proposed poorly soluble lead molecules. there are several methods used for the synthesis of imidazole-containing compounds,and also their various structure reactions offer enormous scope in the field of medicinal chemistry. the imidazole derivatives possess extensive spectrum of biological activities such as antibacterial,anticancer,antitubercular,antifungal,analgesic,and anti-hiv activities. this paper aims to review the biological activities of imidazole during the past years. © 2013 amita verma et al.
آدرس department of pharmaceutical sciences,faculty of health sciences,sam higginbottom institute of agriculture,technology and sciences (deemed to be university),allahabad, India, department of pharmaceutical sciences,faculty of health sciences,sam higginbottom institute of agriculture,technology and sciences (deemed to be university),allahabad, India, department of pharmaceutical sciences,faculty of health sciences,sam higginbottom institute of agriculture,technology and sciences (deemed to be university),allahabad, India
 
     
   
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