Synthesis of new pyrazolo[1,5- a ]pyrimidine,Triazolo[4,3- a ]pyrimidine Derivatives,and Thieno[2,3-b ]pyridine derivatives from sodium 3-(5-Methyl-1-phenyl-1 H -pyrazol-4-yl)-3-oxoprop-1-en-1-olate

Condensation of sodium 3-oxo-3-(1-phenyl-1h-pyrazol-4-yl)prop-1-en-1-olate (2) with several heterocyclic amines,cyanoacetamide,cyanothioacetamide,and 2-cyanoacetohydrazide gives pyrazolo[1,5-a]pyrimidines (5a-d),pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine (9),benzo[4,5]imidazo[1,2-a]pyrimidine (10),[1,2,4]triazolo[1,5-a]pyrimidine (11),and pyridine derivatives (12-14). also,thieno[2,3-b]pyridines (15-18) were synthesized via pyridinethione (13) with α-halo ketones and α-halo ester. structures of the newly synthesized compounds were elucidated by elemental analysis,spectral data,alternative synthetic routes,and chemical transformation whenever possible. © 2013 abdou o. abdelhamid and sobhi m. gomha.