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Synthesis and docking studies of the novel N -(2,2-Di(1H-pyrrol-2-yl)ethyl) adamantane-1-carboxamide,a potential 11 β -HSD1 inhibitor
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نویسنده
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gallardo-alfonzo s. ,ocampo-néstor a.l. ,contreras-celedón c. ,chacón-garcía l.
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منبع
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journal of chemistry - 2014 - دوره : 2014 - شماره : 0
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چکیده
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The synthesis of the novel 1-adamantyl-(n-meso-dipyrrolylmethylene)- carboxamide is described,providing a three-step,two-pot reaction. docking studies with 11β-hsd1 revealed favorable binding interactions with the enzyme. © 2014 salvador gallardo-alfonzo et al.
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آدرس
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laboratorio de diseño molecular,instituto de investigaciones químico biológicas,ciudad universitaria,58033 morelia, Mexico, laboratorio de diseño molecular,instituto de investigaciones químico biológicas,ciudad universitaria,58033 morelia, Mexico, laboratorio de diseño molecular,instituto de investigaciones químico biológicas,ciudad universitaria,58033 morelia, Mexico, laboratorio de diseño molecular,instituto de investigaciones químico biológicas,ciudad universitaria,58033 morelia, Mexico
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Authors
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