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Design,synthesis,and in vitro antiplatelet aggregation activities of ferulic acid derivatives
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نویسنده
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zhang p.-x. ,lin h. ,qu c. ,tang y.-p. ,li n.-g. ,kai j. ,shang g. ,li b. ,zhang l. ,yan h. ,liu p. ,duan j.-a.
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منبع
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journal of chemistry - 2015 - دوره : 2015 - شماره : 0
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چکیده
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In order to discover new compounds with antiplatelet aggregation activities,some ferulic acid (fa) derivatives were designed and synthesized. the in vitro antiplatelet aggregation activities of these compounds were assessed by turbidimetric test. the results showed that the target compound 7f had potent antiplatelet aggregation activity with its ic50 27.6 μmol/l,and 7f can be regarded as a novel potent antiplatelet aggregation candidate. © 2015 peng-xuan zhang et al.
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آدرس
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jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China, jiangsu collaborative innovation center of chinese medicine resources industrialization,jiangsu key laboratory for high technology research of tcm formulae,nanjing university of chinese medicine, China
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Authors
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