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Doxycycline degradation by the oxidative Fenton process
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نویسنده
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borghi a.a. ,silva m.f. ,al arni s. ,converti a. ,palma m.s.a.
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منبع
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journal of chemistry - 2015 - دوره : 2015 - شماره : 0
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چکیده
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Doxycycline is a broad-spectrum tetracycline occurring in domestic,industrial,and rural effluents,whose main drawback is the increasing emergence of resistant bacteria. this antibiotic could be degraded by the so-called fenton process,consisting in the oxidation of organic pollutants by oxygen peroxide (h in the presence of fe2+. experiments were performed according to an experimental rotational central composite design to investigate the influence of temperature (0-40.0°c),hconcentration (100-900 mg/l),and fe2+ concentration (5-120 mg/l) on residual doxycycline and total organic carbon concentrations. whereas the final residual doxycycline concentration ranged from 0 to 55.8 mg/l,the oxidation process proved unable to reduce the total organic carbon by more than 30%. the best operating conditions were concentrations of hand fe2+ of 611 and 25 mg/l,respectively,and temperature of 35.0°c,but the analysis of variance revealed that only the first variable exerted a statistically significant effect on the residual doxycycline concentration. these results suggest possible application of this process in the treatment of doxycycline-containing effluents and may be used as starting basis to treat tetracycline-contaminated effluents. © 2015 alexandre a. borghi et al.
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آدرس
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department of biochemical and pharmaceutical technology,faculty of pharmaceutical sciences,university of são paulo,avenida prof. lineu prestes 580,são paulo, Brazil, biological science center,federal university of pernambuco,cidade universitária,avenue prof. moraes rego 1235,recife, Brazil, department of chemical engineering,king saud university,p.o. box 800, Saudi Arabia, department of civil,chemical and environmental engineering,pole of chemical engineering,genoa university,via opera pia 15, Italy, department of biochemical and pharmaceutical technology,faculty of pharmaceutical sciences,university of são paulo,avenida prof. lineu prestes 580,são paulo, Brazil
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Authors
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