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Reaction of nitrilimines with pyruvaldehyde hydrazones: Synthesis and antimicrobial evaluation of some new 1,2,4-triazole derivatives
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نویسنده
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dalloul h.m.
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منبع
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journal of chemistry - 2015 - دوره : 2015 - شماره : 0
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چکیده
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A new series of 1,3,4,5,5-pentasubstituted-1,2,4-triazoles (4a-j,6a-j) have been synthesized by the 1,3-dipolar cycloaddition of suitable nitrilimines 2 to pyruvaldehyde (2-oxopropanal) hydrazones having (coph,coome,cooet,me/me,and me/ph) groups 3 and 5. both analytical and spectroscopical data of all the synthesized compounds are in full agreement with the proposed structures. the microbial features of the synthesized compounds were studied by a known method. © 2015 hany m. dalloul.
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آدرس
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department of chemistry,faculty of applied science,al-aqsa university of gaza,p.o. box 4051, Palestine
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Authors
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