Rapid and Efficient Synthesis of ω-Alkylenediphosphoric Acids from Phosphorus Oxychloride

The aim of this investigation was to develop an efficient,rapid,and selective method for the synthesis of ω-alkylenediphosphoric acids (ho)2(o)p-o-(ch2)n-o-p(o)(oh)2 from reaction of several diols with phosphorus oxychloride. the reaction was investigated using three methodologies: (i) presence of a base,(ii) classical heating,and (iii) use of microwave irradiation. influence of reaction temperature and molar ratio of reagents,as well as the nature of the solvent,was studied using these three different methods. copyright © 2016 dalila meziane et al.