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Hybrid Nanomaterials Based on Iron Oxide Nanoparticles and Mesoporous Silica Nanoparticles: Overcoming Challenges in Current Cancer Treatments
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نویسنده
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alvarez-berrios m.p. ,sosa-cintron n. ,rodriguez-lugo m. ,juneja r. ,vivero-escoto j.l.
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منبع
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journal of chemistry - 2016 - دوره : 2016 - شماره : 0
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چکیده
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The current approaches used for the treatment of cancer face some clinical limitations such as induction of severe side effects,multidrug resistance (mdr),and low specificity toward metastatic cancer cells. hybrid nanomaterials hold a great potential to overcome all these challenges. among hybrid nanoparticles,those based on mesoporous silica and iron oxide nanoparticles (msns and ionps) have gained a privileged place in the biomedical field because of their outstanding properties. there are many studies demonstrating their effectiveness as drug delivery systems,nanoheaters,and imaging contrast agents. this review summarizes the advances related to the utilization of ionps and msns for reducing side effects,overcoming mdr,and inhibiting metastasis. furthermore,we give a future perspective of the clinical application of these technologies. � 2016 merlis p. alvarez-berrios et al.
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آدرس
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department of science and technology,inter american university of puerto rico,ponce campus,ponce,pr, United States, department of science and technology,inter american university of puerto rico,ponce campus,ponce,pr, United States, department of science and technology,inter american university of puerto rico,ponce campus,ponce,pr, United States, department of chemistry,university of north carolina at charlotte,charlotte,nc, United States, department of chemistry,university of north carolina at charlotte,charlotte,nc,united states,center for biomedical engineering and science,university of north carolina at charlotte,charlotte,nc, United States
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Authors
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