Synthesis of isoxazolopyridines and spirooxindoles under ultrasonic irradiation and evaluation of their antioxidant activity

New polycyclic-fused isoxazolo[4,5-e]pyridines and spirooxindoles were obtained via multicomponent reaction of 5-amino-3-methylisoxazole,indan-1,3-dione,and aromatic aldehydes and reaction of 5-amino-3-methylisoxazole,isatin,and β-diketones in the presence of (±)-camphor-10-sulfonic acid as an effective and nontoxic organocatalyst under ultrasound-promoted conditions. the antioxidant activity of the novel synthesized compounds was studied. © 2017 emel pelit.