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Voltammetric determination of homocysteine using multiwall carbon nanotube paste electrode in the presence of chlorpromazine as a mediator
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نویسنده
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gholami-orimi f. ,taleshi f. ,biparva p. ,karimi-maleh h. ,beitollahi h. ,ebrahimi h.r. ,shamshiri m. ,bagheri h. ,fouladgar m. ,taherkhani a.
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منبع
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journal of analytical methods in chemistry - 2012 - دوره : 2012 - شماره : 0
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چکیده
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We propose chlorpromazine (chp) as a new mediator for the rapid,sensitive,and highly selective voltammetric determination of homocysteine (hcy) using multiwall carbon nanotube paste electrode (mwcntpe). the experimental results showed that the carbon nanotube paste electrode has a highly electrocatalytic activity for the oxidation of hcy in the presence of chp as a mediator. cyclic voltammetry,double potential step chronoamperometry,and square wave voltammetry (swv) are used to investigate the suitability of chp at the surface of mwcntpe as a mediator for the electrocatalytic oxidation of hcy in aqueous solutions. the kinetic parameters of the system,including electron transfer coefficient,and catalytic rate constant were also determined using the electrochemical approaches. in addition,swv was used for quantitative analysis. swv showed wide linear dynamic range (0.1-210.0m hcy) with a detection limit of 0.08m hcy. finally,this method was also examined as a selective,simple,and precise electrochemical sensor for the determination of hcy in real samples. copyright 2012 fathali gholami-orimi et al.
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آدرس
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department of chemisty,qaemshahr branch,islamic azad university, ایران, department of applied science,qaemshahr branch,islamic azad university, ایران, department of nanotechnology,langaroud branch,islamic azad university, ایران, department of chemistry,science and research branch,islamic azad university, ایران, environment department,research institute of environmental sciences,international center for science,high technology and environmental sciences, ایران, department of chemistry,majlesi branch,islamic azad university, ایران, isfahan university of medical sciences, ایران, department of chemisty,takestan branch,islamic azad university, ایران, department of biochemistry,falavarjan branch,islamic azad university, ایران, department of physics,takestan branch,islamic azad university, ایران
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Authors
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