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The Relationship between Intramuscular Adipose Tissue,Functional Mobility,and Strength in Postmenopausal Women with and without Type 2 Diabetes
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نویسنده
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pritchard j.m. ,karampatos s. ,beattie k.a. ,giangregorio l.m. ,ioannidis g. ,atkinson s.a. ,thabane l. ,gerstein h. ,punthakee z. ,adachi j.d. ,papaioannou a.
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منبع
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journal of aging research - 2015 - دوره : 2015 - شماره : 0
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چکیده
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Objectives. to determine (1) whether intramuscular adipose tissue (intramat) differs between women with and without type 2 diabetes and (2) the association between intramat and mobility and strength. methods. 59 women ≥ 65 years with and without type 2 diabetes were included. a 1-tesla mri was used to acquire images of the leg. timed-up-and-go (tug) and grip strength were measured. regression was used to determine associations between the following: (1) type 2 diabetes and intramat (covariates: age,ethnicity,bmi,waist: hip ratio,and energy expenditure),(2) intramat and tug (covariates: diabetes,age,bmi,and energy expenditure),and (3) intramat and grip strength (covariates: diabetes,age,height,and lean mass). results. women with diabetes had more intramat. after adjustment,intramat was similar between groups (diabetes mean [sd] = 13.2 [1.4]%,controls 11.8 [1.3]%,p = 0.515). intramat was related to tug and grip strength,but the relationships became nonsignificant after adjustment for covariates (difference/percent intramat [95% ci]: tug = 0.041 seconds [-0.079-0.161],p = 0.498,grip strength = -0.144 kg [-0.335-0.066],p = 0.175). conclusions. intramat alone may not be a clinically important predictor of functional mobility and strength; however,whether losses in functional mobility and strength are promoted by intramat accumulation should be explored. © 2015 janet m. pritchard et al.
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آدرس
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geriatric education and research in aging sciences (geras) centre,st. peter's hospital,88 maplewood avenue,hamilton,on,canada,department of medicine,mcmaster university,1280 main street west,hamilton, Canada, geriatric education and research in aging sciences (geras) centre,st. peter's hospital,88 maplewood avenue,hamilton,on,canada,department of medicine,mcmaster university,1280 main street west,hamilton, Canada, department of medicine,mcmaster university,1280 main street west,hamilton,on,canada,charlton medical centre,25 charlton avenue east,hamilton, Canada, department of kinesiology,university of waterloo,200 university avenue west,waterloo, Canada, geriatric education and research in aging sciences (geras) centre,st. peter's hospital,88 maplewood avenue,hamilton,on,canada,department of medicine,mcmaster university,1280 main street west,hamilton,on,canada,charlton medical centre,25 charlton avenue east,hamilton, Canada, department of pediatrics,mcmaster university,1280 main street west,hamilton, Canada, department of clinical epidemiology and biostatistics,mcmaster university,1280 main street west,hamilton, Canada, department of medicine,mcmaster university,1280 main street west,hamilton,on,canada,department of clinical epidemiology and biostatistics,mcmaster university,1280 main street west,hamilton, Canada, department of medicine,mcmaster university,1280 main street west,hamilton, Canada, department of medicine,mcmaster university,1280 main street west,hamilton,on,canada,charlton medical centre,25 charlton avenue east,hamilton, Canada, geriatric education and research in aging sciences (geras) centre,st. peter's hospital,88 maplewood avenue,hamilton,on,canada,department of medicine,mcmaster university,1280 main street west,hamilton, Canada
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Authors
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