Clinical Outcomes of Pulmonary Valve Replacement Surgery in Pediatrics: A Single-Center Experience Long-Term Study

Introduction: heart valve disease in pediatricsis an increasing global concern, especially in developing countries. this study aims to determine the clinical outcomes of pulmonary valve replacement (pvr) surgery in pediatrics. methods: the authors retrospectively identified all pediatrics undergoing pvr surgery at imam reza hospital (mashhad, iran) between 2000 and 2020. their medical records were reviewed for demographic characteristics, clinical data (intra-operative and postoperative), and follow-up results. echocardiography and electrocardiography were performedonall patients before the surgery and periodically after the surgery. results: among 50 pediatrics undergoing surgical pvr, 38 (76%) were female and others were male (14%), with a mean age of 10.39±5.31 years. the leading cause of pvr was the tetralogy of fallot. there was a significant relationship between age at the time of surgery and the size of the pulmonary valve(p=0.02).there were also statistically significant differences between qtc intervals before and after surgery (p=0.001). further more, there was a significant correlation between qtc intervals before and after surgery and the ageof pediatrics at the time of surgery (p=0.01, r=-0.6).there was also a statistically significant relationship between the icu stay (p=0.01) and the weaning time of the mechanical ventilation (p=0.03). conclusion: it is recommended that this procedure ispostponed as much as possible to decrease postoperative life-threatening events in pediatrics.in addition, if this surgery is conducted with good surgical and nursing management, it can be safe with low complications among other cardiac valve procedures