successful treatment of acute hepatitis c virus (hcv) infection with interferon-free regimen in a renal transplant patient: the first case report

Introduction: hepatitis c virus (hcv) is considered a major public health problem and in the organ transplant subjects, particularly. the classical interferon/ribavirin regimen is unadvisable for renal transplant patients due to intolerability and adverse effects. case presentation: here, the first case of successful treatment of acute hcv in renal transplant patient is described. a 24-week course of sofosbuvir plus ribavirin was given to a 41- year-old male patient with renal transplant who was diagnosed with acute hcv. the patient was treated successfully without major side effects and without undesirable interaction with immunosuppressive medications. conclusions: this is the first case report regarding the treatment of acute hcv in renal transplant subject using sofosbuvir-containing regimen. more studies are needed to investigate the treatment of acute hcv with the use of new medications especially in the organ transplant subjects.