relationship of meteorological variable and cerebrovascular events: an ecological time series study

Background: climatic conditions contribute to changes in red blood cells, thrombocyte count, andblood pressure. in cold weather, blood viscosity increases, but increasing body temperature raisescoagulation factors. also, plasma fibrinogen concentrations are higher in older patients. all of thesefactors can contribute to the incidence of stroke.objectives: our purpose was to assess the relationships between metrological factors and the rateof stroke patients in the north of iran.materials & methods: we used a time-series analysis to investigate the association betweenmetrological factors and hospital admission of cerebrovascular events from 2014 to 2019 usingdistributed lag nonlinear models.results: hot temperature (≥34°c) was significantly associated with an increased risk of strokeadmission. in the general population, severe cold (≤0°c) was significantly related to the risk of stroke onthe third day after exposure (relative risk [rr]=1.017; 95% confidence interval [ci], 1.00%-1.035%).also, a low temperature of 7°c on 5-6 lag days was significantly associated with the risk of stroke. therisk of stroke hospital admission was not significantly associated with low humidity. humidity with alow percentage (8%-9%) two days after exposure was significantly related to the risk of intracerebralhemorrhage (rr=5.089; 95% ci, 1.002%-25.835% ) (rr=4.841; 95% ci, 1.014%-23.109%),respectively.conclusion: the results show that hot and cold temperatures are associated with stroke admission,and low humidity increases the risk of intracranial hemorrhage. this study suggests that changes inmeteorological variables can raise the risk of stroke and exacerbate the pathogenicity in vulnerablepeople to these diseases.