a case of recovered severe rhino-orbito-cerebral mucormycosis

Background: mucormycosis is a rare disease with high morbidity and mortality, and its diagnosisis difficult and often delayed. also, the disease tends to progress rapidly. therefore, urgent surgicaland medical intervention is lifesaving.case presentation: a 24-year-old woman with diabetes since 3 months ago presented withexcessive tearing in her left eye, unilateral headache with epistaxis, and loss of consciousness atrazi hospital, rasht city, iran, in june 2021. a clinical and pathologic diagnosis of mucormycosiswas established. imaging the head and paranasal sinuses revealed extensive involvement of thebrain, paranasal sinuses, and left orbit. treatment with liposomal amphotericin b (5 mg/kg) wasadministered for about 50 days until discharge. during the treatment period, the patient underwentseveral surgical procedures, such as enucleation of the left eye, surgery on soft and hard palates,sinuses, and neurosurgery for debridement of necrotizing tissues. after 50 days of intensive medicaland surgical treatments, the patient was recovered and discharged. conclusion: in the era of the covid-19 pandemic, many diabetic patients acquire that infection. physicians caring for these patients should be alert to mucormycosis as a complication of severeor mild covid-19 infection. early diagnostic and therapeutic interventions could be lifesaving forthese patients.