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   Exosomes: Future Perspective in Neurodegenerative Diseases  
   
نویسنده Alidoust Leila ,Jafari Adele
منبع Caspian Journal Of Neurological Sciences - 2020 - دوره : 6 - شماره : 4 - صفحه:251 -258
چکیده    Neurodegeneration is a progressive and irreversible loss of neuronal cells in specific regions of the brain. alzheimer diseases (ad) parkinson disease (pd) are the most common forms of neurodegenerative diseases in older people. exosomes are extracellular nanovesicles that have a key role in physiological processes such as intercellular communication, cell migration, angiogenesis, and anti-tumor immunity. mounting evidence indicates the role of exosomes in neurodegenerative disorders as possible carriers of disease particles. they have several different potential applications thanks to their unique structure and functions. the present review summarizes recent studies on exosome potentials as a biomarker and therapeutic tool in neurodegenerative diseases. it also provides an overview of the structure and function of exosomes.
کلیدواژه Exosome ,Neurodegenerative Disease ,Microrna ,Biomarker
آدرس Guilan University Of Medical Sciences, Faculty Of Medicine, Department Of Medical Genetics, Iran, Guilan University Of Medical Sciences, Neuroscience Research Center, Faculty Of Medicine, Department Of Physiology, Iran
پست الکترونیکی jafari.adele@gmail.com; a_jafari@gums.ac.ir
 
     
   
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