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comparing the quality of life in patients with multiple sclerosis consuming fingolimod and cinnovex
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نویسنده
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saberi alia ,hatamian hamidreza ,ghayeghran amirreza ,mollahosseni fatemeh ,aghayari sheikh neshin saeideh ,noroozi guilandehi sama ,rezaei sajjad ,shafaei fatemeh
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منبع
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caspian journal of neurological sciences - 2019 - دوره : 5 - شماره : 19 - صفحه:151 -160
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چکیده
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Background: multiple sclerosis (ms) is a chronic demyelinating, inflammatory, and degenerative disease of the central nervous system. ms gradually limits and deteriorates the patients ' quality of life.objectives: this study aimed to evaluate and compare the quality of life in patients with ms consuming fingolimod and cinnovex. materials methods: in an analytical crosssectional study, 106 patients with relapsing-remitting ms (rrms) referred to specialized neurology clinics of guilan university of medical sciences were selected for the study using a convenience sampling method (52 patients consuming fingolimod and 54 patients consuming cinnovex). then, we collected their demographic information and medical profile. the patients were assessed by the hamburg quality of life questionnaire in ms. the obtained data were analyzed in spss v. 22 using the chisquare test, independent ttest, mann-whitney u, oneway and multivariate analysis of covariance.results: there was a significant difference between the two groups in terms of age, number of attacks in the last 6 months, and educational level (p<0.05). after controlling confounding variables, it was found that consumers of fingolimod had a better quality of life. at the subscales level, this difference was significant only in the mood dimension (f=6.931, p=0.011, η=0.12).conclusion: patients consuming fingolimod reported a better quality of life compared to consumers of cinnovex. this improvement was mainly found in mood scores.
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کلیدواژه
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multiple sclerosis (ms) ,quality of life (qol) ,fingolimod hydrochloride
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آدرس
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guilan university of medical sciences, neuroscience research center, poursina hospital, department of neurology, iran, guilan university of medical sciences, poursina hospital, department of neurology, iran, guilan university of medical sciences, poursina hospital, department of neurology, iran, guilan university of medical sciences, poursina hospital, department of neurology, iran, guilan university of medical sciences, student research committee, neuroscience research center, school of medicine, iran, guilan university of medical sciences, student research committee, neuroscience research center, school of medicine, iran, university of guilan, department of psychology, iran, guilan university of medical sciences, neuroscience research center, poursina hospital, iran
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Authors
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