Non-Adherence To Disease-Modifying Treatments in Patients With Multiple Sclerosis

Background: multiple sclerosis (ms) is a debilitating disease of the central nervous system. usually, long-term ms medications are injected intramuscularly or subcutaneously, making them intolerable for many ms patients. objectives: in the present study, the rate and the causes of non-adherence to ms disease-modifying drugs (dmds) were assessed in patients with ms. materials and methods: two hundred and three ms patients of guilan ms society were interviewed demographic and clinical data of the patients were collected. results: among the 203 patients, 73.9% were female. the mean±sd age of the patients was 32.47±9.15. non-adherence to dmds was due to side effects (21.7%) and requests of the families (21.7%) or ineffectiveness (17.4%). significant association was seen between the non-adherence to dmds and gender (p=0.015) and relapses (p=0.021). conclusion: the evidence from the present study suggests that there is a high rate of non-adherence to dmds in ms patients in guilan.