Effect of Elastic Resistance Training and Vitamin D on Systemic Inflammation Indices in Untrained Men: A Clinical Trial

Background: recent studies demonstrate the ability of vitamin d to reduce inflammation and oxidative stress. objectives: the current study aimed at examining the effect of vitamin d supplementation on systemic inflammation markers during an eight-week elastic resistance training (ert) on untrained men. materials and methods: forty healthy males with no experience in resistance training were assigned to elastic training—vitamin d (ed, n=10), elastic resistance training—placebo (ep, n=10), vitamin d (vd, n=10), and control (con, n=10) groups. ert was performed with eight exercises three times a week on non-consecutive days for eight weeks. also, the subjects in the ed, vd, and ep groups consumed 50,000 iu vitamin d or placebo once every two weeks. blood samples were collected before and 72 hours after the last session of eight weeks of ert for measuring concentration of tumor necrosis factor-alpha (tnf-alpha), interleukin-6 (il-6), and c reactive protein (crp). results: it is found that ed elicited a significant reduction in il6 than vd (p<0.05) and control (p<0.05). also, there is a significant difference between ep group and vd (p<0.05) and control ones (p<0.05). however, there is no significant difference between ed and ep in the variables mentioned (p<0.05). also, it was observed that there was no statistical significant alteration in crp concentration between pre- and post-training (p>0.05). conclusion: finally, we can claim that the combination of elastic resistance training with vitamin d did not have extra advantages in attenuation of systemic inflammatory indices when compared with the training alone.