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apoptosis in hair and skin: a review
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نویسنده
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ahmadi ashtiani hamid reza ,zakizadeh samin ,khanahmadi maryam ,nilforoushzadeh mohammad ali ,zare sona
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منبع
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journal of skin and stem cell - 2018 - دوره : 5 - شماره : 4 - صفحه:1 -12
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چکیده
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Context: the current study aimed at evaluating the role of apoptosis in hair and skin conditions. evidence acquisition: in the current study, the role of apoptosis in the occurrence or treatment of the apoptosis-associated disease was investigated. likewise, the mechanism of apoptosis pathways occurring in the skin and hair cells was also reviewed. conclusions: melanocyte and follicular epithelial cells are the most sensitive cells to apoptosis, whereas dermal papilla cells, fibroblasts, and some of keratinocytes are the most resistance cells to apoptosis. according to the current review study, novel drugs can be designed based on stimulation or inhibition of the apoptosis such as bcl2, p53 and caspase inhibitors.
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کلیدواژه
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apoptosis ,skin ,hair ,fibroblast ,melanocyte ,keratinocyte
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آدرس
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islamic azad university, pharmaceutical sciences branch, faculty of pharmacy, department of basic sciences, iran, islamic azad university, pharmaceutical sciences branch, faculty of pharmacy, department of basic sciences, iran, islamic azad university, pharmaceutical sciences branch, faculty of pharmacy, department of basic sciences, iran, tehran university of medical science, skin and stem cell research center, iran, tehran university of medical science, skin and stem cell research center, iran. islamic azad university, hamedan branch, faculty of basic science, department of biology, iran
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پست الکترونیکی
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sonazare@gmail.com
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Authors
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