the role of wharton’s jelly mesenchymal stem cells in skin reconstruction

Context: stem cell therapy, especially in the segment of mesenchymal stem cells (mscs), is one of the most promising areas of regenerative medicine.[evidence acquisition according to research conducted by various researchers, wharton’s jelly mesenchymal stem cells (wjmscs) have several advantages compared to others sources, in regenerative medicine: wjmscs are more primary cells; wjmscs can be easily isolated and without invasive procedures; wjmscs have no ethical problems; wjmscs are more cost effective than other sources of mscs. also, wjmscs were demonstrated to express stem cell mesenchymal markers.[results]similar to bone marrow mscs, wjmscs express major histocompatibility complex (mhc) class i molecules.[conclusions]although the aforementioned challenges must still be addressed, the potential of wjmscs in skin regenerative clinical treatments is promising.