anti-malassezia ige in patients with atopic eczema before and after treatment with ketoconazole shampoo

Background: treatment of some fungi species would result in the improvement of atopic eczema. objectives: in this study, the anti-malassezia ige in patients with atopic eczema before and after treatment with a ketoconazole shampoo was determined. methods: in this before-after investigation, 20consecutive patients with atopic dermatitis referring to a teaching hospital in tehran, iran, in 2015 were enrolled. a ketoconazole shampoo was administered two times a week each time for 5 - 10 minutes. the treatment was used for two months and monthly evaluations were done. the total ige level and anti-malassezia ige were compared at the beginning and the end of the study. results: the results demonstrated that there was a statistically significant difference in the total ig-e level and anti-malassezia ige before and after treatment with ketoconazole. conclusions: according to the obtained results in this study, it may be concluded that ketoconazole would result in decreased anti-malassezia ige and total ige level in patients with atopic eczema.