reed syndrome; multiple cutaneous and uterine leiomyomatosis

Introduction: reed syndrome is a rare autosomal dominant disorder with a genetic defect in the fumarate hydratase. patients with reed syndrome have multiple cutaneous leiomyomas, uterine leiomyomas or leiomyosarcomas with increased risk of renal carcinoma. case presentation: the current study presented a 57-year-old female with multiple cutaneous and uterine leiomyomatosis with a positive family history. she and her family had no evidence of renal carcinoma. conclusions: multiple skin leiomyomas could be considered as a cutaneous marker for uterine leiomyomatosis and possible renal cell carcinoma in the familial presentations.