angioedema following spinal anesthesia with bupivacaine in a pregnant woman undergoing caesarian: a case report and review of potential etiologies

Spinal anesthesia with bupivacaine is widely used for cesarean sections but can rarely cause angioedema, a rapid swelling of deep tissues that may lead to airway obstruction. this case report presents the occurrence of angioedema in a pregnant woman with postoperative hyper ige levels following spinal anesthesia. it highlights the intricate interplay between drug sensitivity, immune dysregulation, and the physiological changes associated with pregnancy. we present a case of a 32-year-old woman with post-operative hyper ige levels who developed angioedema shortly after getting spinal anesthesia with bupivacaine for a cesarean section. it should be noted that the patient had no prior history of allergic reactions, making the case particularly interesting and challenging. this report's goal is to: 1. report details of the clinical presentation, management, and outcome of this unusual patient; 2. investigate the potential etiologies of angioedema, with a focus on the relationship between bupivacaine sensitivity, hyper ige, and other possible factors; and 3. highlight the challenges in diagnosis and management when facing angioedema in patients with atypical presentations.