effects of rosmarinus officinalis plant extract on trichomonas vaginalis parasites and candida albicans under laboratory conditions: an experimental study

Background: as we know metronidazole is a selective treatment for trichomoniasis, however, it has many side effects, and, on the other hand, it is important to try finding natural alternative treatments.objectives: the aim of this study was to investigate the effects of rosmarinus officinalis plant extract on trichomonas vaginalis parasites and candida albicans under laboratory conditions.methods: in this experimental study, rosmarinus officinalis methanolic extracts were prepared. the anti-trichomoniasis effect was evaluated at concentrations of 0.1, 0.01, 0.001, 0.0004, 0.0002, and 0.0001 μg/ml in tyis33 culture media and resulted data were analyzed by anova.results: the results of this study showed that in the concentration of 0.001 at 4 hours, the parasite was spherical and inactivated, while at concentrations of 0.0004, 0.001, 0.01, and 0.1 in 1 hour. the results of this study showed that rosmarinus officinalis extract in concentration of 100 µg/ml has an inhibitory effect on candida albicans, so that the highest inhibitory diameter was 18.3 ± 0.9 mm while two other strains exhibit resistance and no inhibitory zones.conclusions: the results of this study showed that rosemary extract inhibits the growth of trichomonas vaginalis and candida albicans that can be used to treat infections.