standardization of molecular diagnostic of the entc and ent e staphylococcus aureus isolated from human infections in zabol

Background: staphylococcus aureus is one of the most important causes of hospital infections around the world. it has been found in various studies, that 15% - 18% of the staphylococcus aureus strains isolated from different sources are capable of producing enterotoxin. the aim of this study is identifying staphylococcus aureus, types c and e, which produce enterotoxin, from human infections in zabol by pcr. methods: the present study was conducted on 60 urine samples in a 1-year period. samples were randomly collected from different parts of the city of zabol and transferred to the university lab in a minimum period of time by maintaining cold conditions. dna extraction was performed and pcr was done for enterotoxin e and c. results: the results of this study showed that isolated s. aureus was resistant to antibiotics including cefazolin (7.3%), doxycycline (12.10%), erythromycin (22.3%), rifampin (9.7%), ciprofloxacin (18.10%), and co-trimoxazole (14.5%). the results of this study showed that the prevalence of enterotoxin e gene in s. aureus samples was 1.5%. conclusions: regarding the importance of s. aureus secretes, 2 types of toxins with super antigen activity, enterotoxins, of which there are 6 antigenic types (named se-a, b, c, d, e and g). in case of expression of enterotoxin genes, rapid treatment of the infection seems to be necessary.