relationship between shift work and lipid profiles: a prospective cohort study with application of ordinal multilevel modeling

Introduction:a very limited evidences are available that considered the relationship between shift work (sw) and lipid variables. objectives: as the importance of this subject, this prospectively cohort study examines the association between sw and body mass index (bmi) and lipid profiles among male workers using multilevel ordinal model methods: this five years prospective cohort study has been conducted in random selected workers (using cluster sampling) who work in esfahan’s mobarakeh steel company (emsc) (iran) between 2011 and 2015. results: the study sample included 1626 male workers (mean age=41.5). among these subjects, 652 (40.01%), 183 (11.3%) and 791 (48.6%) were day workers, weekly rotating shift workers and routinely rotating. after controlling for several confounding variables, except hdl and cholesterol, the odds ratio for high hdl was decreased by 26% (or=0.74, p<0.001) and increased for tg by 36% in weekly rotating shift workers compared to day workers. conclusion: since weekly rotating shift workers had higher mean value of tg in their serum compared to day workers, they should limit eating high-fat diets in order to decrease risk of cvd.