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acute efavirenz intoxication in a 16-year-old hiv negative girl: a case report and literature review
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نویسنده
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moghimi minoo ,nekoukar zahra ,khosravi navid
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منبع
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pharmaceutical and biomedical research - 2024 - دوره : 10 - شماره : 1 - صفحه:73 -78
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چکیده
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Background: there are only rare case reports that revealed the efavirenz (efv) toxicity.case report: this study presents an acute intoxication with 12 g of efavirenz in a 16-year-old healthy girl whose main problem was dose-dependent neurotoxicity. no other serious efv-related side effects were seen. previous serious side effects of efv were observed in hiv-infected patients who underwent long-term combination drug therapy. conclusion: accordingly, in terms of the key clinical messages, serious adverse effects of efavirenz are expected to be observed in long-term use in combination with other antiretroviral drugs.
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کلیدواژه
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efavirenz ,intoxication ,neurotoxicity ,human immunodeficiency virus ,toxicology
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آدرس
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mazandaran university of medical sciences, faculty of pharmacy, department of clinical pharmacy, iran, mazandaran university of medical sciences, faculty of pharmacy, department of clinical pharmacy, iran, mazandaran university of medical sciences, school of medicine, department of emergency medicine, iran. mazandaran university of medical sciences, razi hospital, department of emergency medicine, iran
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پست الکترونیکی
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n.khosravi@mazums.ac.ir
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Authors
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