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Fatal Pulmonary Scedosporium Aurantiacum Infection in A Patient After Near-Drowning: A Case Report
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نویسنده
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Ghasemian Roya ,Bandegani Azadeh ,Kermani Firoozeh ,Faeli Leila ,Roohi Behrad ,Yosefi Abdolmaleki Elham ,Hedayati Mohammad T. ,Roilides Emmanuel ,Shokohi Tahereh
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منبع
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Current Medical Mycology - 2021 - دوره : 7 - شماره : 4 - صفحه:38 -42
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چکیده
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Background and purpose: scedosporium spp. is a saprophytic fungus that may cause invasive pulmonary infection due to the aspiration of contaminated water in both immunosuppressed and immunocompetent hosts. case report: herein, we report a fatal case of pulmonary infection caused by scedosporium species associated with a car crash and near-drowning in a sewage canal. scedosporium aurantiacum isolated from bronchoalveolar lavage was identified by pcr-sequencing of β-tubulin genes. the minimum inhibitory concentration values for amphotericin b, itraconazole, posaconazole, isavuconazole were >16 μg/ml, and >8 μg/ml for anidulafungin, micafungin, and caspofungin. voriconazole was found to be the most active agent with a mic of 1 μg/ml. conclusion: this report, as the first case of pulmonary scedosporiosis after near-drowning in iran, highlights the importance of high suspicion in near-drowning victims, prompt identification of scedosporium spp., and early initiation of appropriate antifungal therapy.
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کلیدواژه
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Antifungal Susceptibility Test ,Amphotericin B ,Invasive Pulmonary Infection ,Near-Drowning ,Scedosporium Aurantiacum ,Voriconazole
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آدرس
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Mazandaran University Of Medical Sciences, Antimicrobial Resistance Research Center, Communicable Diseases Institute, Iran, Mazandaran University Of Medical Sciences, Student Research Committee, Iran, Mazandaran University OfMedical Sciences, School Of Medicine, Invasive Fungi Research Centre (Ifrc), Department Of Medical Mycology, Iran, Mazandaran University Of Medical Sciences, Student Research Committee, Iran, Mazandaran University Of Medical Sciences, Student Research Committee, Iran, Mazandaran University Of Medical Sciences, School Of Medicine, Department Of Internal Medicine, Iran, Mazandaran University Of Medical Sciences, Invasive Fungi Research Center, Communicable Diseases Institute, School Of Medicine, Department Of Medical Mycology, Iran, Aristotle University, Faculty Of Medicine, School Of Health Sciences, Infectious Diseases Section, 3rd Department Of Pediatrics, Greece, Mazandaran University Of Medical Sciences, Invasive Fungi Research Center, Communicable Diseases Institute, School Of Medicine, Department Of Medical Mycology, Iran
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پست الکترونیکی
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shokohi.tahereh@gmail.com
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Authors
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