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Snakin: Structure,roles and applications of a plant antimicrobial peptide
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نویسنده
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oliveira-lima m. ,benko-iseppon a.m. ,neto j.r.c.f. ,rodríguez-decuadro s. ,kido e.a. ,crovella s. ,pandolfi v.
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منبع
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current protein and peptide science - 2017 - دوره : 18 - شماره : 1
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چکیده
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Snakins are plant antimicrobial peptides (amps) of the snakin/gasa family,formed by three distinct regions: an n-terminal signal peptide; a variable site; and the gasa domain in the cterminal region composed by twelve conserved cysteine residues that contribute to the biochemical stability of the molecule. these peptides are known to play different roles in response to a variety of biotic (i.e.,induced by bacteria,fungi and nematode pathogens) and abiotic (salinity,drought and ros) stressors,as well as in crosstalk promoted by plant hormones,with emphasis on abscisic and salicylic acid (aba and sa,respectively). such properties make snakin/gasa members promising biotechnological sources for potential therapeutic and agricultural applications. however,information regarding their tertiary structure,mode of action and function are not yet completely elucidated. the present review presents aspects of snakin structure,expression,functional studies and perspectives about the potential applications for agricultural and medical purposes. © 2017 bentham science publishers.
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کلیدواژه
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Crosstalk; Cysteine-bridges; Snakin/GASA domain; Stress response
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آدرس
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federal university of pernambuco,center of biological sciences,department of genetics,laboratory of genetics and vegetal biotechnology,av. prof. moraes rêgo 1235,recife,pe, Brazil, federal university of pernambuco,center of biological sciences,department of genetics,laboratory of genetics and vegetal biotechnology,av. prof. moraes rêgo 1235,recife,pe, Brazil, federal university of pernambuco,center of biological sciences,department of genetics,laboratory of genetics and vegetal biotechnology,av. prof. moraes rêgo 1235,recife,pe, Brazil, universidad de la república,facultad de agronomía,departamento de biología vegetal,garzón 780,montevideo, Uruguay, federal university of pernambuco,center of biological sciences,department of genetics,laboratory of genetics and vegetal biotechnology,av. prof. moraes rêgo 1235,recife,pe, Brazil, federal university of pernambuco,center of biological sciences,department of genetics,laboratory of genetics and vegetal biotechnology,av. prof. moraes rêgo 1235,recife,pe,brazil,genetic service,irccs burlo garofolo and department of developmental and reproductive sciences,university of trieste -via dell’istria,65/1- 34137,trieste, Italy, federal university of pernambuco,center of biological sciences,department of genetics,laboratory of genetics and vegetal biotechnology,av. prof. moraes rêgo 1235,recife,pe, Brazil
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Authors
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