Nail matrix arrest during the course of hand,foot,and mouth disease: Evaluation of onychomadesis cases [El,ayak,ağız hastalığı seyrinde tırnak matriks arresti: Onikomadezis olgularının değerlendirilmesi]

Objective: hand,foot,and mouth disease (hfmd) is an infectious disease that is particularly common in children. hfmd is clinically characterized by erosive stomatitis that occurs with a vesicular and maculopapular rash. this rash is frequently observed in the hands and feet and sometimes in the gluteal and inguinal regions. it is known that various enteroviruses,including coxsackievirus,echovirus,and enterovirus 71,may be causative agents. hfmd is usually a self-limited and benign condition; however,fatal cardiopulmonary and neurological complications may be occasionally observed cases with enterovirus 71 infection. onychomadesis is defined as proximal nail plate separation with a temporary arrest in the activity of the nail matrix. in this article,we present four onychomadesis cases that occurred as a rare complication of hfmd. material and methods: in the present study,we included patients who presented with onychomadesis after hfmd diagnosis between january 2013 and december 2014 at the hacettepe university faculty of medicine,pediatric infectious diseases outpatient clinic. results: four onychomadesis cases diagnosed with hfmd were included in this study. all patients were males,and their ages were 11 years,21 months,7 years,and 27 months. the underlying disease in one patient was all in remission. none of the patients had a history of skin disease. the periods from hfmd diagnosis to nail changes were 3 weeks and 2 months for the first two patients and 4 weeks for the other two patients. onychomadesis was improved without any treatment during the follow-up. conclusion: onychomadesis after hfmd is a benign clinical disorder. in the differential diagnosis of pediatric cases of onychomadesis,the patients should be queried about a history of hfmd. © 2015 by pediatric infectious diseases society.