Preemptive effect of dexketoprophen trometamol or paracetamol/tramadol combination on postoperative analgesia [Total di̇z protezi̇nde preempti̇f deksketoprofen trometamol veya parasetamol/tramadol kombi̇nasyonun postoperati̇f analjezi̇ye etki̇si̇]

Objective: the use of tramadol and non-steroidal anti-inflammatory drugs for postoperative pain is common. in this randomized,double blind study,we aimed to evaluate the analgesic efficacy of dexketoprophen trometamol and paracetamol/tramadol combination in 24 hour tramadol consumption of the patients,their vas values,extra analgesic need,and side effects who undergo total knee prothesis under general anesthesia. methods: after the approval of the ethics committee,the study was performed on 56 patients (asa i-ii) planned for total knee prothesis. the patients who were randomly allocated into two equal groups received oral dexketoprophen trometamol (group a) or paracetamol/tramadol combination (group z),1 hour before the operation. all patients received standard general anesthesia and received 1 mg kg-1 tramadol intravenously before extubation. all patients received patient controlled analgesia with tramadol,and their 24 hour tramadol consumption,vas scores,extra analgesic need and side effects,demographic variables and duration of operation were recorded. results: in group z,median bolus doses of tramadol given was significantly high (p=0.007),but median attempt was significantly low (p=0.004). additive analgesic need was statistically low and late in group z (p<0.001). vas scores were statistically low in z group (p<0.001) compared to a group. conclusion: it has been observed that preemptive consumption of paracetamol/tramadol combination is associated with a decrease in vas scores,less and late consumption of additive analgesics in postoperative patients.