Effects of combination of prilocaine and magnesium in intravenous regional anesthesia [İntravenöz rejyonal anestezi̇de pri̇lokai̇ne magnezyum eklenmesi̇ni̇n etki̇leri̇]

Objective: in this study we aimed to compare sensory and motor block onset and recovery times,anesthesia and analgesia quality,effects on pain and sedation and side effects of intravenous regional anesthesia (ivra) with prilocaine and prilocaine + magnesium sulphate combination. method: ivra was achieved with 3 mg kg-1 prilocaine diluated with saline to a total of 35-45 ml in group i (n=23) and 3 mg kg-1 prilocaine plus 10 ml of % 15 magnesium sulphate diluated with saline to total of 35-45 ml in group ii (n=23). vas,and rss were recorded. time to first intraoperative fentanyl request and total fentanyl dose were noted. when vas≥4,paracetamol was administrated. time to first postoperative paracetamol request and total paracetamol dose were noted. patients were followed up during operation and postoperative 24 hours with respect to advers events. results: sensory and motor block onset times were significantly shorter and recovery times were significantly longer in group ii (p<0,05). tourniquet pain began significantly later and administirated fentanyl amount was smaller in group ii than group i (p<0,05). time to first analgesic request was significantly longer and administrated paracetamol amount was smaller in group ii (p<0,05). in group ii,vas values were significantly lower than group i at intraoperative and postoperative period (p<0,05). when adverse events were evaluated,all patients experienced a mild and short-lived injection pain due to magnesium injection in group ii. in group i,3 patients (13,04%) experienced short-lived metalic taste and one patient (4,34%) experienced short-lived tinnitus owing to local anesthesic. conclusion: we have concluded that magnesium sulphate as an adjuvant to prilocaine has decreased tourniquet pain,perioperative and postoperative analgesic requirement in ivra; thus it provides beter anesthesia and analgesia quality in appropriate patients.