The effect of preoperative anxiety on propofol consumption under entropy monitorization [Preoperatif anksiyetenin entropi monitorizasyonu altinda propofol tüketimi üzerine etkisi]

Objective: preoperative anxiety is associated with adverse effects on intraoperative anesthetic requirement,hemodynamic,neuroendocrine changes and postoperative recovery and pain. in this study,we aimed to evaluate the effects of preoperative anxiety on hemodynamics and anesthetic requirement in female patients under general anesthesia whose anesthetic depth is monitorized by entropy. method: after approval of the ethics committee and informed consent of patients; stai form tx-1/2 was administered to 50 patients. propofol and remifentanil infusions were administered at induction and during maintenance; so as to keep entropy between 40-60. hemodynamic parameters and total anesthetic agent consumption were recorded throughout the study. results: levels of trait anxiety and state anxiety were 39.4±11.2 and 42.5±8.8,respectively. time to have entropy 40-60; and the amount of propofol consumption were not statistically different between high and low anxiety groups. the hemodynamic parameters did not change significantly in either high or low anxiety groups (p > 0.05). conclusion: we determined that the differences between trait and state anxiety levels did not affect anesthesia induction time,anesthetic agent consumption and hemodynamic parameters. however,more clinical studies with monitorization of anesthetic depth are required to lighten the contradictory results obtained from the studies investigating this subject in the literature.