impact of medical factors on mortality in patients with end-stage renal disease in the west of iran: a prospective study

Background and aims: end-stage renal disease (esrd) is a pervasive global health challenge with high mortality rates. this prospective study aimed to identify medical factors influencing mortality in esrd patients. methods: data from 149 esrd patients registered at imam khomeini hospital in kermanshah were analyzed. only patients with a minimum of one-year follow-up were included. univariate and multiple regression analyses were employed, and model evaluation utilized indicators such as the area under the receiver operating characteristic (roc) curve, sensitivity, and specificity. results: among 149 esrd patients, 88 (59.1%) were male, and 37 (24.7%) experienced mortality. the average age of deceased patients was 63.59±15.74 years. chronic glomerulonephritis was the underlying cause in 72 (48.3%) participants. multiple regression revealed that age, diabetes, and a history of heart failure significantly correlated with mortality. esrd patients with diabetes faced a 2.47-fold increased risk of death (95% confidence interval: 1.10 - 5.55). the model exhibited an area under the curve (auc) of 0.70, with sensitivity and specificity of 51.35% and 75%, respectively. conclusion: given the chronic nature of esrd and elevated mortality, particularly among diabetic patients, intensified monitoring efforts are crucial for the prevention and management of diabetes in this population.