periodontal condition and total antioxidant status in serum among patients with polycystic ovarian syndrome

Background and aims: the most prevalent endocrine disease with unknown etiology among women in their fertility period is polycystic ovarian syndrome (pcos). the disease causes some changes in oxidative stress system, which in turn, is associated with such diseases as metabolic syndrome, diabetes, cardiovascular diseases, and periodontitis. the present study investigated periodontal status and total antioxidant status in serum of women with pcos. materials and methods: in this cross-sectional, analytic study eighty women, 40 with pcos as cases and 40 infertile women without pcos participated. interview, oral examination and radiographs, and laboratory tests served as data collection tools. body mass index (bmi), community periodontal index (cpi), periodontal disease index (pdi), bone loss, and total anti-oxidant status (tas) in serum of the participants were measured. chi-squre test, mann-whithney test, and linear regression served for statistical analysis. results: while in case group 21 patients had bone loss, in control group bone loss was found in 11 pateints (p=0.022). the distribution of maximum cpi score among cases was significantly different from that among controls in that more frequent higher scores existed among cases (p=0.016). the mean pdi in case and control group was 6.23±3.3 and 4.48±2.6, respectively (p=0.015). in general linear model the level of serum tas was significantly associated with cpi (p=0.039) and bmi (p=0.019). conclusion: women with pcos seem to be more susceptible to periodontal disease compared to other women. this calls for comprehensive periodontal care and regular dental visits for patient with pcos.