the relationship between anosmia and ageusia with biochemical markers, severity, and duration of the disease in patients with covid-19

Introduction: due to the increasing prevalence of covid-19 and its effects on the sense of taste and smell, we analyzed blood electrolyte levels and biomarkers in covid-19 patients who have a sign of anosmia and ageusia in zanjan, iran, and its relationship with biochemical blood indicators. materials and methods: the retrospective study included all hospitalized patients with confirmed covid-19. we registered laboratory parameters. a questionnaire that validity and reliability have already been confirmed was used to assess anosmia and ageusia. statistical analysis was evaluated using a bivariate bayesian logistic regression in the binomial distribution. results: a total of 450 covid-19 patients completed the study (221 females). the mean age of the patients was 56.36±17.34 years. 31.8% and 24.9% of patients reported anosmia and ageusia. there was no significant relationship between anosmia and ageusia with age, gender, place of hospitalization, marriage status, duration of hospitalization, and ct scan (p<0.05). the male’s platelet was 18.72 lower than the female’s (p=0.002). male’s c-reactive protein was 4.96 units higher than female (p=0.002). in hospitalized persons for less than four days and people under 39 years of age, crp levels were lower (p=0.001, p=0.019 respectively). the levels of lactate dehydrogenase in patients with anosmia were 51.72 units less than in patients without anosmia (p=0.010). conclusion: these results suggest that anosmia and ageusia are prevalent symptoms in iranian covid-19 patients. more information on serum biomarkers would help us to establish a greater degree of accuracy on this matter.