central giant cell granuloma mimicking a malignant lesion of mandible: a case report

Central giant cell granuloma (cgcg) is a relatively uncommon benign osseous lesion with sometimesaggressive nature. the nature of this lesion is unknown and although the exact cause isunclear, the three theories about possibility of its nature are: developmental anomaly, reactivelesion or benign neoplasm. histologically by presence of multinucleated giant cells within a stromaof spindle-shaped mesenchymal and fibro vascular connective tissue along with containing ofhemorrhagic areas is characterized. this case report presents the diagnosis and management of acgcg in a 50 years-old man with biopsy and surgical treatments. the lesion involve the left sideof mandibular. diagnosis plan was designed based on the combination of pathology and imaging.finally after en bloc resection of involved regions of mandible, a titanium plate prosthesis was usedfor the jaw reconstruction. since some of cgcg lesions can be highly invasive and inclinically andradiographic features can mimic as malignancy lesions.